C.E. Hull & Company
Calvin E. Hull began his career in proprietary medicine ni New York City around 1850. His partnership with Albert Spencer to produce a line of Hull and Spencer medicines came to an end in 1856 or '57, and Hull does not surface again until 1867-68 in Connecticut. He used general issue proprietary stamps until April of 1870, when his private die stamp was first delivered. It was last issued on December 4, 1882.
319,400 were printed on old paper, 445,810 on silk paper and 491,093 on pink and watermarked papers. The copy above is on silk paper.